CLINICAL SIGNIFICANCE OF IMMUNE IMBALANCE AND AUTOIMMUNITY IN NERVOUS SYSTEM DISORDERS (NSDs)

Vijendra K SINGH

Abstract


In recent years, the role of immune imbalance and autoimmunity has been experimentally demonstrated in nervous system disorders (NSDs) that include Alzheimer’s disease, autism, obsessive-compulsive disorder (OCD), tics and Tourette’s syndrome, schizophrenia, and some other NSDs. And yet, these NSDs are never counted as autoimmune diseases. Deriving from the rapidly expanding know­ledge of neuro-immunology and auto­immune diseases, for example multiple scle­rosis (MS), the author of this mini-review strongly recom­mends that these NSDs should be included while tallying the number of autoim­mune diseases. This effort will help create an updated global database of all autoimmune diseases as well as it should help treat millions of patients who are suffering from debilitating NSDs for which there is no known cure or treatment currently.

Keywords


CNS disorders; autoimmune diseases; neuro-immune diseases

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References


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DOI: http://dx.doi.org/10.1515/JSER-2015-0014

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